Welcome Dr. Lina Santaguida!

Welcome Dr. Lina Santaguida !  

Dr. Santaguida is an Assistant Professor in McMaster’s Department of Research Methods, Evidence & Impact and will be joining the team.

Beyond a PhD from U of T, she has vast experience in methodology in systematic review, successful grants with CIHR, AHRQ and other agencies, ‘real world’ research experience including management of large projects, and a host of other skills.

A very warm welcome, Lina!  We look forward to working together with you to improve the health of women and infants! 

“Researchers find best strategy to prevent chronic lung disease in preterm infants”

The study “Association of Noninvasive Ventilation Strategies With Mortality and Bronchopulmonary Dysplasia Among Preterm Infants: A Systematic Review and Meta-analysis” was published in the Journal of the American Medical Association (JAMA) in August 2016. This study was co-authored by Dr. Sarah McDonald, the originator of the study, and Dr. Tetsuya Isayama, the lead author.

Together, they compared different ventilation strategies in order to determine how to best ventilate preterm infants and concluded that Less Invasive Surfactant Administration (LISA) was the best.

The study was featured in several online news sites:

  1. Medscape- Reuter Health Information: http://www.medscape.com/viewarticle/867270
  2. Medical Xpress: http://medicalxpress.com/news/2016-08-lisa-strategy-chronic-lung-disease.html
  3. Hamilton Spectator: http://www.thespec.com/news-story/6811732-mcmaster-finds-best-way-to-ventilate-preemies/
  4. Clinical Advisors: http://www.clinicaladvisor.com/pulmonology-information-center/preventing-bronchopulmonary-dysplasia-in-preterm-infants/article/516479/
  5. Deutsches Ärzteblatt: http://www.aerzteblatt.de/nachrichten/69976/Fruehgeburten-Sieben-Beatmungsmethoden-im-Vergleich
  6. McMaster University: http://fhs.mcmaster.ca/main/news/news_2016/chronic_lung_html

 

Article: Isayama T, Iwami H, McDonald S, Beyene J. Association of noninvasive ventilation strategies with mortality and bronchopulmonary dysplasia among preterm infants. A systematic review and meta-analysis. JAMA. 2016;316(6):611-624; doi: 10.1001/jama.2016.10708

Bon Voyage Alexander!

Last week, the team held a celebration for Alexander and Marinela. Marinela has recently begun her OBGYN residency at McMaster and we wish her the best on this endeavour. We thank Alexander, who has been with the team for 3 years, for all his dedication and hard work. Bon voyage! We look forward to their ongoing work with the team!

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AM900 CHML Radio Feature

On July 6, AM900 CHML Radio featured an interview with Dr. Sarah McDonald, hosted by Jamie West. The interview ran at 12:35 pm that afternoon and discussed Dr. McDonald’s Canadian Institutes of Health Research (CIHR) funded study on predicting and preventing premature labour.

The same day, the Hamilton Spectator also published an article discussing the study: https://www.hamiltonnews.com/news-story/7408680-mcmaster-researchers-trying-to-predict-premature-birth-and-prevent-it/

SOGC Annual Clinical and Scientific Conference 2017

Alexander and Dr. McDonald traveled to Ottawa at the end of June for the 2017 Annual Clinical and Scientific Conference hosted by the Society of Obstetricians and Gynecologists of Canada (SOGC).

Congratulations to Alexander for his superb poster presentation, “Preterm birth prevention in twin pregnancies with progesterone, pessary, or cerclage: a meta-analysis”! With his fantastic presentation skills, practice, and feedback from the team, Alexander was well prepared to make the knowledge translation as effective as possible!

“McMaster researchers trying to predict premature birth and prevent it”

On July 6, an article in the Hamilton Spectator, “McMaster researchers trying to predict premature birth and prevent it”, featured Dr. Sarah McDonald’s CIHR-funded study on preterm birth.

The study involves analyzing data from thousands of births in Ontario in order to identify factors in the mother’s medical history or in the current pregnancy to better identify women at risk of preterm birth. This will be an important step in the process of developing a clinical tool to assist clinicians in targeting care.

The full article is available at: https://www.hamiltonnews.com/news-story/7408680-mcmaster-researchers-trying-to-predict-premature-birth-and-prevent-it/

“CIHR grants awarded to two studies looking at preemies”

On July 4, McMaster Faculty of Health Sciences published an article, “CIHR grants awarded to two studies looking at preemies”, including a feature on Dr. Sarah McDonald and her work on risk assessment prediction models for preterm birth.

Preterm birth is the leading cause of death and long-term disability in infants, affecting 1 in 12 births in Canada. Dr. Mcdonald’s work aims to create a tool to assist clinicians in identifying which women are at risk of preterm birth to better target care.

The full article is available at:  https://fhs.mcmaster.ca/main/news/news_2017/CIHR_grants_awarded_preemies.html

Spring 2017 Presentations

Dr. McDonald  enjoyed presenting at a number of forums these past months:

“Inter-hospital Rounds” Southern Ontario Obstetrics Network (SOON), St. Michaels Hospital, April 7th, 2017 – Toronto, ON

“Canada’s New Preterm Birth Network: UBC’s pivotal role in this opportunity for OB, MFM, Neonatology, Follow-up & Health Economics to Innovate Together”, as the keynote speaker at the University of British Columbia’s Academic Research Day, Vancouver, BC March 8, 2017

“Revisiting Antenatal Corticosteroids:  Tailoring the Timing of a Powerful Drug” UBC Obstetrics and Gynaecology 17th Annual Academic Day, University of British Columbia, Vancouver, BC March 9, 2017

“Improving Outcomes for Preterm Infants and their Families: A Canadian Collaborative Network”, Meeting with MFMs for input into variable collection, Evidenced Based Improvement in Care (EPIC) meeting, Canadian National Perinatal Research Meeting, Toronto, Feb 16, 2017

“Rethinking our Approach to Antenatal Corticosteroids: Educational Rounds”, Guelph General Hospital-  January 20, 2017

“Non-Invasive Prenatal Screening: Tips and Pitfalls from Our First 1000 cases at McMaster” Neural Information Processing Systems (NIPS) talk for Drs. Nwebube, Narine & Gai, Family Medicine and Midwifery, West Lincoln Hospital, Grimsby, ON January 18, 2017

“Antenatal Corticosteroids: To give or not give in the Late Preterm or Term Time Periods?” Neo/MFM Department Rounds, McMaster University, January 13, 2017

CIHR Grants

With a team of 100 clinicians, researchers, organizations, policy makers and patient representatives, Dr. McDonald was delighted to be part of the writing team for a Canadian Institutes of Health Research (CIHR) Preterm Birth Network Team Grant “Improving Outcomes for Preterm Infants and their Families: A Canadian Collaborative Network” November 1, 2016 – October 31, 2021.

Nominated Principal Investigator:  Dr. Prakesh Shah
Co-Principal Investigator: Dr. Sarah D. McDonald and 8 other co-PI, with 90 co-investigators.

Dr. McDonald was pleased to contribute as a Co-investigator to Dr. K. S. Joseph’s Successful Canadian Institutes of Health Research (CIHR) Team Grant: Perinatal Healthcare System Improvement. Awarded October 2016 – October 2021.

4th Annual CNPRM

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Dr. Grabovac presented a poster presentation at the 4th Annual Canadian National Perinatal Research Meeting (CNPRM) of work done with Feng YY, Jarde A, Seo Y, Grabovac M, Powell A, Nwebube M, McDonald SD, “How often are progesterone, pessary and cerclage being used for prevention of preterm birth in primary, secondary and tertiary Canadian centres?”, which found that approximately 1 in 4 women at risk of preterm birth from a previous preterm birth or short cervix were offered prevention, while 1 in 6 was offered progesterone.  The conference was held in Montebello, QC February 14-17 2017.

cnprm2017singletonbreech

Dr. Grabovac presented a plenary oral on “What is the safest mode of delivery for extremely preterm breech infants: a systematic review and meta-analyses?”, work she completed with Dr. Jehan Karim, a PGY-3 in our department who did a research elective with Dr. McDonald. Importantly, she and Dr. Karim found that Cesarean section is associated with an approximate 40% reduction in the odds of death and severe intraventricular hemorrhage in actively resuscitated breech singleton infants before 28 weeks.

cnprm2017interprovincial

Dr. Grabovac also presented an oral presentation of an interprovincial comparison of recent data, work done in conjunction with the provincial perinatal research programs through S Dzakpasu, N Chapinal, M Guo, C Woolcott, P Murphy and Dr. McDonald which found, increasing proportions of women from west to east begin pregnancy with excess weight or gain too much weight during pregnancy. Excess GWG was a larger contributor to LGA than either overweight or obese BMI. Similarly, the contribution of inadequate GWG to SGA exceeded that of underweight BMI.

Dr. McDonald was excited to be part of a CIHR grant from which came research entitled “Caesarean section and health care utilization in the offspring”. Alexander Nikolas MacLellan, Christy G. Woolcott, Linda Dodds, Bryan Maguire, Sarah McDonald, Stefan Kuhle. 4th Annual Canadian National Perinatal Research Meeting (CNPRM), Montebello, QC   February 14-17 2017.

What a fruitful week!